漫画18

食品科学与工程系

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  • 邓华祥
  • 性别:男
  • 职称:副教授
  • 硕导/博导:硕导
  • 最高学位:博士
  • 最高学历:研究生
  • 邮箱:[email protected]
  • 研究方向:人工智能辅助微生物智能制造高值天然产物

个人简介

(1)HuXX, YanY, Liu WJ, Liu J, Fan T-P,Deng HX*, Cai YJ*.Advances and perspectives on pharmacological activities and mechanisms of the monoterpene borneol.Phytomedicine2024, 132:155848.(共同通,IF=6.7一区,)

(1)Liu D, Gou LB, SunTT, Liu J, Fan T-P,Deng HX*, Cai YJ*. Characterization and application of a stationary phase promoter library fromSerratia marcescens.ACSSyntheticBioliogy2024, 13(3):969-972. (共同通讯,IF=4.7中科院一区,)

(1)Deng HX,Yu H, Deng YW, Qiu YL, Li FF, Wang XR, He JH, Liang WY, Lan YQ, Qiao LJ, Zhang ZY, Zhang YF, Keasling JD*, Luo XZ*. Pathway evolution through a bottlenecking-debottlenecking strategy and machine learning-aided flux balancing.Advanced Science.2024, 11(14):e2306935.(第一作者IF=15.1一区)

(1)Yu H,Deng HX, He J, Keasling JD, Luo XZ*. UniKP: a unified framework for the prediction of enzyme kinetic parameters.Nature Communications.2023, 14(1):8211. (共同一作IF=16.6一区,)

(1)Deng HX*, Liang XX, Liu JB, Zheng XH, Fan T-P, Cai YJ*. Advances and perspectives on perylenequinone biosynthesis.Frontiers in Microbiology.2022, 13: 1070110. (第一作者IF=6.064,二区)

(1)Deng HX*, Liang WY, Fan T-P, Zheng XH, Cai YJ*. Modular engineering ofShiraia bambusicolafor hypocrellin production through an efficient CRISPR system.International Journal of Biological Macromolecules.2020, 165(Pt A): 796-803. (第一作者,IF=6.953一区)

(1)Deng HX*, Bai YJ, Fan T-P, Zheng XH, Cai YJ*. Advanced strategy for metabolite exploration in filamentous fungi.Critical Reviews in Biotechnology.2020, 40(2): 1-19. (第一作者,IF=8.429一区)Deng HX, Jia P, Jiang J, Bai Y, Fan T-P, Zheng X,Cai YJ*.Expression and characterisation of feruloyl esterases fromLactobacillus fermentumJN248 and release of ferulic acid from wheat bran.International Journal of Biological Macromolecules. 2019, 138:272-277. (第一作者,IF=5.162一区)

教育经历

2018.04-2019.04,加州大学伯克利分校,合成生物学,联合培养博士

2008.08-2012.06,四川轻化工大学,生物技术,理学学士

2012.08-2019.06,江南大学,发酵工程,工学博士

工作经历

2024.07-至今,漫画18 ,漫画18 ,副教授

2021.06-2024.06,中国科学院深圳先进研究院,合成生物学,助理研究员

2019.06-2021.06,江南大学,漫画18 ,博士后

社会兼职

生物化学与分子生物学会员

主要项目情况

(1)国自然科学基金青年项目:竹红菌素合成漆酶的迭代定向进化及其催化机制解析,主持

(2)深圳先进院院优青C类:基于自动化与机器学习技术合成黄酮类高附加值底盘微生物 ,主持

(3)博士后留深资助项目:基于合成生物学技术构建黄酮类底盘,主持

(4)江苏省青年基金:高产竹红菌素的氧化胁迫智能调控系统构建及机制解析,主持

(5)中国博士后面上基金:高产竹红菌素底盘微生物的构建,主持

代表性论文

(1)HuXX, YanY, Liu WJ, Liu J, Fan T-P,Deng HX*, Cai YJ*.Advances and perspectives on pharmacological activities and mechanisms of the monoterpene borneol.Phytomedicine2024, 132:155848.(共同通,IF=6.7一区,)

(2)Liu D, Gou LB, SunTT, Liu J, Fan T-P,Deng HX*, Cai YJ*. Characterization and application of a stationary phase promoter library fromSerratia marcescens.ACSSyntheticBioliogy2024, 13(3):969-972. (共同通讯,IF=4.7中科院一区,)

(3)Deng HX,Yu H, Deng YW, Qiu YL, Li FF, Wang XR, He JH, Liang WY, Lan YQ, Qiao LJ, Zhang ZY, Zhang YF, Keasling JD*, Luo XZ*. Pathway evolution through a bottlenecking-debottlenecking strategy and machine learning-aided flux balancing.Advanced Science.2024, 11(14):e2306935.(第一作者IF=15.1一区)

(4)Yu H,Deng HX, He J, Keasling JD, Luo XZ*. UniKP: a unified framework for the prediction of enzyme kinetic parameters.Nature Communications.2023, 14(1):8211. (共同一作IF=16.6一区,)

(5)Deng HX*, Liang XX, Liu JB, Zheng XH, Fan T-P, Cai YJ*. Advances and perspectives on perylenequinone biosynthesis.Frontiers in Microbiology.2022, 13: 1070110. (第一作者IF=6.064,二区)

(6)Deng HX*, Liang WY, Fan T-P, Zheng XH, Cai YJ*. Modular engineering ofShiraia bambusicolafor hypocrellin production through an efficient CRISPR system.International Journal of Biological Macromolecules.2020, 165(Pt A): 796-803. (第一作者,IF=6.953一区)

(7)Deng HX*, Bai YJ, Fan T-P, Zheng XH, Cai YJ*. Advanced strategy for metabolite exploration in filamentous fungi.Critical Reviews in Biotechnology.2020, 40(2): 1-19. (第一作者,IF=8.429一区)

(8)Deng HX, Jia P, Jiang J, Bai Y, Fan T-P, Zheng X,Cai YJ*.Expression and characterisation of feruloyl esterases fromLactobacillus fermentumJN248 and release of ferulic acid from wheat bran.International Journal of Biological Macromolecules. 2019, 138:272-277. (第一作者,IF=5.162一区)